Timeline
Achievements, Personal events, Historical background. 1846Use of ether for general anesthesia byWilliam T.G. Morton 1852September 23 - Born in New York City1867March 16 - Joseph Lister publishes series of articles in The Lancet on the "Antiseptic Principle of the Practice of Surgery" describing the use of carbolic acid(phenol) on surgical wounds to reduce the incidence of gangrene. 1870 Graduates from Phillips Academy AndoverCaptain of first American 11-playerfootball team- This is played against Eton College, two years prior to the first annualYale-Harvard football game.
- Other sports: rowing, gymnastics,baseball (shortstop).
- A multi-sport athlete, Halsted is a mediocre student.
- Does show not any interest in medicine until senior year, when his interest is piqued by Gray's Anatomyand a physiology textbook by John C. Dalton.
- Halsted is assigned to assist John C. Dalton himself and anatomist and surgery professor Henry B. Sands as a mentor.
- Upon discovering his sister nearly dead from a postpartum hemorrhage, Halsted boldly draws his own blood and injects it into his sister, saving her life.
- Halsted implies knowledge of blood rejection possibility.
- Visiting his mother in Albany, he finds her exhibiting Charcot's triad (fever, right upper quadrant pain, jaundice).
- Among the first to suggest the replacement of blood during surgery as well as autotransfusion andintravenous saline for use in shock, although these ideas forgotten for dozens of years before becoming the standard of care.
- Halsted and colleagues develop severe cocaine addiction.
- He only publishes one paper on the topic, in the New York Medical Journal
- Halstead's writing is indubitably stained by the evidence of intoxication.
- Pupil Harvey Cushing never suspects the cocaine habit.
- This period between fighting cocaine addiction and beginning Johns Hopkins marks an abrupt personality change for Halsted from bold and vivacious extrovert to diffident, anti-social introvert.
- In later years, Halsted becomes addicted to morphine, also unsuspected by nearly everyone. This was revealed in a book by William Osler: The Inner History of Johns Hopkins Hospital.
- Contemporaries here include William H. Welch, William Osler, Howard Kelly, Franklin Mall, William Howell, and John Jacob Abel.
- Head operating room nurse and wife-to-be Caroline Hampton developsdermatitis from chemicals used to disinfect hands for surgery.
- This prompts Halsted to hire theGoodyear Rubber Company to manufacture thin gloves that will not interfere with necessary sensitivity.
- Halsted only later realizes the impact of gloves on antisepsis.
- Inguinal hernias had been previously associated with high mortality rates.
- Although infrequently performed, the Halsted II remains the gold standardtoday, with post-operative complication rates only slightly improved from Halsted's 7%.
- The married couple are described as opposites in appearance.
- A dandy garbed in European tailored suits and Parisian cobbled boots, Halsted is known to dress impeccably, even sending his dress shirts yearly to Paris to be laundered.
- Mrs. Halsted's style is described as austere.
- Halsted and wife never had children, but they did have Dachshunds, including Sisley (or Sisly,) Fritz, Nip and Tuck. In 1915, he wrote that Nip had died just a few weeks after Sisly (MacCallum, 1930, p 120).
- They live separately in a three-story brick home in Baltimore: Halsted on the second floor, Caroline and canines on the third.
- Each summer they spend one month at High Hampton, Caroline's 2000-acre (8 km²) North Carolina family estate.
- This is due to the efforts of four young Baltimoreans- -all women--who raised the money needed to open the school only on the condition that women be granted equal opportunity admission.
- These women were university trustees' daughters: M. Carey Thomas, Mary Elizabeth Garrett,Mary Gwinn, and Elizabeth King.
- Garrett contributed an additional amount with additional strings: these established pre-requisites for medical school admission.
- Former students Heuer and Mont Reid perform operation.
- They use Halsted's own technique in closing the bile duct.
- Complications include agastrointestinal hemorrhage and post-operative pneumonia, which was the cause of death.